What is an eosinophil ?

They can be friend or foe.

In a healthy individual typically 1 to 5% of white blood cells are eosinophils (pronounced ee-oh-sin-oh-fills), which far from being an enemy play an important role in your immune system. Produced in the bone marrow they circulate through your blood vessels for 8-12 hours around the body before migrating into a tissue, where they remain for 1-2 weeks.

This proinflammatory cell contains around 200 large granules of enzymes and proteins which break open (degranulate) and release their toxic contents when the Eosinophil is activated. Their function is to move to the inflamed areas, trapping substances and killing cells.

 

This process can occur when fighting bacteria, parasites, allergic reactions and other inflammatory responses.

The eosinophil has many varied roles some of which are yet to be discovered. Current research shows that they can be both helpful and harmful, they may even be part of organ formation (e. g. postgestational mammary gland development).

 

However, when a person has abnormally elevated numbers of eosinophils in their digestive system, tissues, organs, and/or bloodstream, without a known cause, he or she may have an eosinophil-associated disease.

 

 

It is from the eosin staining of the cells under a microscope and them becoming a deep pink that they get their name eosinophil.

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Last updated 23/01/20 ©EOS Network 2020 All rights reserved