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  • The Evolving Understanding of Eosinophilic-Associated Type 2 Inflammatory Diseases

    The Evolving Understanding of Eosinophilic-Associated Type 2 Inflammatory Diseases

    Eosinophilic-Associated Diseases (EADs) extend beyond the gut, linking other inflammatory T2 conditions like EoE, asthma, and atopic dermatitis. Learn about evolving research, diagnosis challenges, and targeted biologic treatments that are transforming patient care. Read more

  1. Home
  2. Biologics for Eosinophilic Diseases: Latest News & Research

Biologics for Eosinophilic Diseases: Latest News & Research

Biologics are targeted therapies that act on type 2 inflammation pathways and offer new treatment options across Eosinophilic-Associated Diseases (EADs). This section brings together the latest research, trial results, approvals, and access updates. 
The Evolving Understanding of Eosinophilic-Associated Type 2 Inflammatory Diseases

The Evolving Understanding of Eosinophilic-Associated Type 2 Inflammatory Diseases

Eosinophilic-Associated Diseases (EADs) extend beyond the gut, linking other inflammatory T2 conditions like EoE, asthma, and atopic dermatitis. Learn about evolving research, diagnosis challenges, and targeted biologic treatments that are transforming patient care. Read more

Published: 4th March, 2025

Updated: 14th May, 2026

Author: Olena Filatova

Benralizumab for Eosinophilic Asthma and COPD Exacerbations. ABRA Study Findings

Benralizumab for Eosinophilic Asthma and COPD Exacerbations. ABRA Study Findings

Discover the study findings comparing benralizumab (ABRA) and prednisolone in treating eosinophilic exacerbations of asthma and COPD. Read more

Published: 28th November, 2024

Updated: 9th September, 2025

Author: Olena Filatova

Access to Dupixent (Dupilumab) Treatment in the UK Explained

Access to Dupixent (Dupilumab) Treatment in the UK Explained

Learn how NICE and SMC policies affect your access to multi-indication drugs like Dupixent® (dupilumab) for EoE in the UK despite its availability worldwide. Discover how EOS Network's advocacy works to influence change for better access. Read more

Published: 14th November, 2024

Updated: 9th September, 2025

Author: Olena Filatova

AstraZeneca’s Fasenra Approved in EU for EGPA

AstraZeneca’s Fasenra Approved in EU for EGPA

Fasenra is now EU-approved for EGPA, offering new hope for patients with relapsing symptoms and high disease burden. Read more

Published: 11th November, 2024

Updated: 9th September, 2025

Author: Olena Filatova

EU Approves Dupixent® (dupilumab) as First Treatment for Young Children with EoE

EU Approves Dupixent® (dupilumab) as First Treatment for Young Children with EoE

Dupixent (dupilumab) becomes the first approved treatment for eosinophilic oesophagitis (EoE) in children aged 1-11 across the EU. Learn more about the study results. Read more

Published: 11th November, 2024

Updated: 9th September, 2025

Author: Olena Filatova

Fasenra Approved in China For Severe Eosinophilic Asthma Patients

Fasenra Approved in China For Severe Eosinophilic Asthma Patients

Fasenra (Benralizumab) gains approval in China for treating severe eosinophilic asthma, offering new hope to millions of patients with limited treatment options. Learn more about this significant advancement Read more

Published: 28th August, 2024

Updated: 9th September, 2025

Author: Olena Filatova

Benralizumab's Efficacy in Reducing Eosinophil Count in EoE. Messina Phase 3 Trial

Benralizumab's Efficacy in Reducing Eosinophil Count in EoE. Messina Phase 3 Trial

Messina Phase 3 trial results show benralizumab reduces eosinophil counts in EoE patients, with no notable improvement in dysphagia symptoms. Read more

Published: 2nd July, 2024

Updated: 9th September, 2025

Author: Olena Filatova

Persistent Asthma Symptoms in Children on Mepolizumab

Persistent Asthma Symptoms in Children on Mepolizumab

Explore a study that aims to understand why some people on eosinophil-directed treatments continue to have Eosinophilic Asthma flare-ups. Read more

Published: 9th April, 2024

Updated: 9th September, 2025

Author: Olena Filatova

Fasenra Outperforms Nucala in EGPA Steroid Reduction: MANDARA Study Findings

Fasenra Outperforms Nucala in EGPA Steroid Reduction: MANDARA Study Findings

Discover how Fasenra outperforms Nucala in treating Granulomatosis with Polyangiitis (EGPA), offering hope for reduced steroid use and improved remission. Read more

Published: 19th March, 2024

Updated: 9th September, 2025

Author: Olena Filatova

FDA Approves Dupixent As EoE Treatment For Children From One to Eleven

FDA Approves Dupixent As EoE Treatment For Children From One to Eleven

FDA has approved Dupixent (dupilumab) for children aged one to eleven, an important step for EoE management in young children and families. Read more

Published: 26th January, 2024

Updated: 9th September, 2025

Author: Olena Filatova

FDA Grants Priority Review for Dupixent (dupilumab) in Treating Eosinophilic Oesophagitis in Children

FDA Grants Priority Review for Dupixent (dupilumab) in Treating Eosinophilic Oesophagitis in Children

Learn more about Dupixent and what impact its approval could have on treating EoE in younger children. Read more

Published: 26th September, 2023

Updated: 15th December, 2025

Author: Olena Filatova

Study: Weekly Doses of Dupilumab Are The Most Effective at Managing Eosinophilic Oesophagitis

Study: Weekly Doses of Dupilumab Are The Most Effective at Managing Eosinophilic Oesophagitis

Recent research shows weekly dupilumab outperforms bi-weekly treatments in managing Eosinophilic Oesophagitis (EoE) symptoms. Read more

Published: 19th September, 2023

Updated: 9th September, 2025

Author: Olena Filatova

What treatments are in pipeline for EoE?

What treatments are in pipeline for EoE?

Learn more about treatments that are going through investigations and trials for treating EoE. Answers CEGIR. Read more

Published: 19th September, 2023

Updated: 9th September, 2025

Author: Olena Filatova

TSLP: A Pathway to Non-Invasive Blood Tests and Targeted Treatments

TSLP: A Pathway to Non-Invasive Blood Tests and Targeted Treatments

Learn how groundbreaking research on Thymic Stromal Lymphopoietin (TSLP) offers hope for more effective and less invasive diagnoses and treatments for eosinophilic diseases like EoE. Read more

Published: 19th September, 2023

Updated: 9th September, 2025

Author: Olena Filatova

Clinical Guidance for the Use of Dupilumab in Eosinophilic Oesophagitis: A Comprehensive Approach

Clinical Guidance for the Use of Dupilumab in Eosinophilic Oesophagitis: A Comprehensive Approach

The latest USA guidance on the use of dupilumab in EoE. Insights into when and how to consider dupilumab as a first-line or step-up therapy, shared decision-making approach and monitoring outcomes. Read more

Published: 26th June, 2023

Updated: 9th September, 2025

Author: Olena Filatova

Dupilumab recommended for EU approval

Dupilumab recommended for EU approval

Dupilumab has been recommended for EU approval by the CHMP for the treatment of eosinophilic oesophagitis (EoE). It is the first biologic drug in the EU indicated for EoE for sufferers aged 12+. Read more

Published: 23rd December, 2022

Updated: 9th September, 2025

Author: Alex Boulding

Dupilumab Maintains Long-Term Efficacy in EoE

Dupilumab Maintains Long-Term Efficacy in EoE

The third part of a trial investigating dupilumab in EoE has found the drug maintains its clinical, symptomatic and histologic efficacy and safety profile up to Week 52 in adults and children over 12+. Read more

Published: 3rd November, 2022

Updated: 6th May, 2026

Author: Alex Boulding

Update on MESSINA EoE Trial

Update on MESSINA EoE Trial

October 2022 - MESSINA trial of Fasenra in EoE patients demonstrated a significant improvement in histological disease remission but not an improvement in dysphagia symptoms. Read more

Published: 31st October, 2022

Updated: 6th May, 2026

Author: Alex Boulding

First UK Patient in MESSINA EoE Trial

First UK Patient in MESSINA EoE Trial

The first UK patient has been recruited for the global MESSINA study for benralizumab for EoE. Find study details and see if you're eligible to take part in the Phase 3 trial. Read more

Published: 27th January, 2022

Updated: 9th September, 2025

Author: Alex Boulding

Dupilumab Improves EoE Symptoms

Dupilumab Improves EoE Symptoms

Mar 2021 - Phase 3 trial shows Dupilumab to improve health-related quality of life and reduces symptom burden in patients with EoE. Read more

Published: 19th March, 2021

Updated: 9th September, 2025

Author: Alex Boulding

Phase 3 trial for Fasenra in EoE begins

Phase 3 trial for Fasenra in EoE begins

Dec 2020 - AstraZeneca has begun its Phase 3 trial evaluating Fasenra in EoE and other eosinophilic diseases. It has also announced a further Phase 3 trial evaluating the drug for EG and EGE. Read more

Published: 22nd December, 2020

Updated: 9th September, 2025

Author: Alex Boulding

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Latest

  • Jorveza® receives interim recommendation as maintenance therapy for EoE in Wales

    Jorveza® receives interim recommendation as maintenance therapy for EoE in Wales

    Wales approves Jorveza as a maintenance therapy for EoE ahead of NICE appraisal. Learn more about Jorveza and EOS Network's role in medical approvals.

  • EoE Treatment Access Survey: Share Your Experience

    EoE Treatment Access Survey: Share Your Experience

    More and more treatments for EoE are being discovered, but not everyone has the same access to them. Help combat treatment inequality by taking part in our survey.

  • Eosinophils beyond the oesophagus: Insights from a 2025 review

    Eosinophils beyond the oesophagus: Insights from a 2025 review

    A recent review explores our current understanding of non-EoE EGIDs and highlights how our approach to diagnosis and treatment is changing.

  • Highlights from the Allergy & Free From Show 2026

    Highlights from the Allergy & Free From Show 2026

    This May, our team had the privilege of exhibiting at the Allergy & Free From Show (AFF) in Birmingham. Discover highlights from the event and save the date for AFF 2027.

Most read

  • What Is An Eosinophilic-Associated Disease (EAD)?

    What Is An Eosinophilic-Associated Disease (EAD)?

    When abnormal levels of eosinophils are found in your body (oesophagus, stomach or intestine/bowel), tissues, blood or other organs without a known cause/diagnosis, further consideration should be given to eosinophilic - associated diseases (EADs).

  • EoE - Eosinophilic Oesophagitis

    EoE - Eosinophilic Oesophagitis

    Learn about Eosinophilic Oesophagitis (EoE), a chronic disease affecting the oesophagus. Discover its symptoms, causes, diagnosis methods, and treatment options at EOS Network.

  • EoE Symptoms and Causes

    EoE Symptoms and Causes

    The symptoms and known causes of eosinophilic oesophagitis (EoE) in children and adults. Links to videos from gastroenterologists and a patient Action Plan for food blockages.

  • EoE Treatment

    EoE Treatment

    An overview of the different types of treatment for Eosinophilic esophagitis (EoE). Includes dietary, allergy, dilatation and drug therapies.

  • Types of Eosinophilic Diseases

    Types of Eosinophilic Diseases

    EGID’S Eosinophilic Gastrointestinal Diseases: EoE Eosinophilic Oesophagitis Esophagitis: Oesophagus EoG Eosinophilic Gastritis: stomach EoN Eosinophilic Enteritis: small intestine EoC Eosinophilic Colitis: large intestine HES Hypereosinophilic Syndrome: blood and any organ  Churg-Strauss Syndrome - Eosinophilic Granulomatosis with Polyangiitis: lungs, sinuses, heart, various organ systems

  • Food Obstruction Patient Action Plan

    Food Obstruction Patient Action Plan

    EoE Food Obstruction Action Plan for Patients and Carers. A free printable resource for those diagnosed with Eosinophilic Oesophagitis.

  • What is an eosinophil?

    What is an eosinophil?

    Learn about eosinophils, their function in the immune system, and their impact on eosinophilic diseases. Discover how EOS Network supports research and provides resources for patients.

  • EoE Diagnosis

    EoE Diagnosis

    How eosinophilic oesophagitis (EoE) is diagnosed, current medical guidelines and more resources for patients and healthcare professionals.

  • Find A Doctor

    EOS Network Global Map to locate a healthcare professional who has a specialist interest in Eosinophilic Oesophagitis (EoE), Eosinophilic Gastritis (EG), Eosinophilic Colitis (EC), Eosinophilic Gastroenteritis (EGID), Hyper Eosinophilic Syndrome HES, previously known as Churg-Strauss Syndrome, now Eosinophilic Granulomatosis Eith Polyangiitis (EGPA)

  • EoE Symptom Tracker

    EoE Symptom Tracker

    EoE Symptom Tracker for Patients and Carers. A free printable resource for those diagnosed with Eosinophilic Oesophagitis. Drinking lots of water when eating? Always last to finish a meal? Difficulty swallowing your food? Avoiding foods?

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Food Obstruction Patient Action Plan

Food Obstruction Patient Action Plan

EoE Food Obstruction Action Plan for Patients and Carers. A free printable resource for those diagnosed with Eosinophilic Oesophagitis. Read more

Published: 26th March, 2021

Updated: 27th May, 2026

Author: Amanda Cordell

EAW 22 - Save the Date!

EAW 22 - Save the Date!

Save the date in your diaries - Eosinophil Awareness Week (EAW) will take place 16th - 22nd May this year! It's an opportunity to promote awareness of EGIDs and show support for those living with eosinophilic diseases. Read more

Published: 27th January, 2022

Updated: 2nd April, 2022

Author: Alex Boulding


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